Replication of two porcine parvovirus isolates at non-permissive temperatures
نویسندگان
چکیده
منابع مشابه
Biology of Porcine Parvovirus (Ungulate parvovirus 1)
Porcine parvovirus (PPV) is among the most important infectious agents causing infertility in pigs. Until recently, it was thought that the virus had low genetic variance, and that prevention of its harmful effect on pig fertility could be well-controlled by vaccination. However, at the beginning of the third millennium, field observations raised concerns about the effectiveness of the availabl...
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The pathogenic parvovirus B19 (B19V) has an extreme tropism for human erythroid progenitor cells. In vitro, only a few erythroid leukemic cell lines (JK-1 and KU812Ep6) or megakaryoblastoid cell lines (UT7/Epo and UT7/Epo-S1) with erythroid characteristics support B19V replication, but these cells are only semipermissive. By using recent advances in generating large numbers of human erythroid p...
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Replicative helicases unwind double-stranded DNA in front of the polymerase and ensure the processivity of DNA synthesis. In Escherichia coli, the helicase loader DnaC as well as factors involved in the formation of the open complex during the initiation of replication and primosomal proteins during the reactivation of arrested replication forks are required to recruit and deposit the replicati...
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In utero inoculation of 15 sows at various stages of gestation with a local strain of porcine parvovirus (PPV) resulted in resorption, abortion or the birth of weak, dead, or mummified foetuses. Histopathological lesions observed in foetuses of sows slaughtered at various post-inoculation intervals consisted of a perivascular inflammatory reaction primarily observed in the brain and kidneys. Th...
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ژورنال
عنوان ژورنال: Archives of Virology
سال: 1990
ISSN: 0304-8608,1432-8798
DOI: 10.1007/bf01316676